Oriental Foods and Herbs. Chemistry and Health Effects by Chi-Tang Ho, Jen-Kun Lin, and Qun Yi Zheng (Eds.)

By Chi-Tang Ho, Jen-Kun Lin, and Qun Yi Zheng (Eds.)

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Harwood Academic Publishers: The Netherlands, 1998; pp 120-122. 86. Lee, K. ; Lin, Y. ; Wu, T. ; Zhang, D. ; Hall, I. ; Chang, J. ; Wu, R. ; Yang, T. H. Planta Medica 1988, 308-311. 87. ; Suffness, M. Pharmac. 1988, 37, 425 and references cited therein. 88. ; Stahelin, H. J. Med. Chem. 1971, 14, 936. 89. ; Marsoni, S. Cancer Treat. Rep. 1984, 68, 1455. 90. , 1983. 91. Etoposide (VP-16) Current Status and New Developments; Issell, B. , Muggia, F. , Carter, S. ; Academic Press: Orlando, FL, p 1984.

1990, 53, 587-595. 74. Nakatani, N. Biofactors 2000, 13, 141-146. 75. Andersen, L. ; Moskaug, J. ; Jacobs, D. ; Blomhoff, R. J. Nutrition 2002, 132, 461-471. 76. Ho, C. ; Rosen, R. ; Huang, M. T. In Food Phytochemicals for Cancer Prevention. T. ,ACSSymposium Series 547; American Chemical Society: Washington, DC, 1994; Vol. II, pp 2-19. 77. Shimamura, T. In Food Phytochemicals for Cancer Prevention. , Huang, M. T. , ACS Symposium Series 547; American Chemical Society: Washington, DC, 1994; Vol. II, pp 101-104.

The guidance document entitled "Guidance for industry Botanical Drug Products" from the Food and Drug Administration of the Uunited States serves to delineate a possible path for researchers and industry to follow for botanical drug development and commercialization. This document further shows an appreciation of the valuable experience of historical use of botanical drugs and the difference between them and synthetic drugs. However, two points should be seriously considered. 1. Logically, chemical fingerprinting plus pharmacological fingerprinting are perhaps the best way, at this time, to provide assurance of product quality and consumer protection.

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