By Keith Cartwright (auth.), John M. Walker, Andrew J. Pollard MD, PhD, Martin C. J. Maiden PhD (eds.)
Neisseria meningitidis is a tremendous reason behind adolescence morbidity and mortality in industrialized international locations and is liable for epidemics of meningococcal meningitis and septic surprise in Africa and Asia. In Meningococcal ailment: tools and Protocols, Andrew Pollard and Martin Maiden assemble a panel of top experts to supply a entire, interdisciplinary survey of modern advances and information approximately this much-feared sickness. The evaluate and methods-based chapters accrued the following supply crucial details for analysis within the medical microbiology laboratory, isolate characterization, scientific administration, and regulate of meningococcal affliction. additionally they learn the immunopathological mechanisms taking place within the acutely unwell, host-pathogen interactions, and the prospective elements of meningococcus chargeable for virulence. A better half quantity, Meningococcal Vaccines, presents designated equipment for the layout and overview of meningococcal vaccines.
finished and authoritative, Meningococcal sickness: equipment and Protocols integrates the elemental technology and the medical and epidemiological facets of this bad infectious ailment to advertise the deeper knowing had to determine novel pursuits for healing interventions and vaccines.
Read or Download Meningococcal Disease: Methods and Protocols PDF
Best nonfiction_9 books
Content material: bankruptcy 1 Transformator (pages 43–201): bankruptcy 2 Allgemeine Betrachtungen uber rotierende elektrische Maschinen (pages 203–281): bankruptcy three Gleichstrommaschine (pages 283–357): bankruptcy four Allgemeine Betrachtungen uber Maschinen mit Drehfeldern als Luftspaltfeld (pages 359–392): bankruptcy five Dreiphasen?
This dissertation makes a speciality of the calculation of shipping coefficients within the subject created in a relativistic heavy-ion collision after chemical freeze-out. This topic may be good approximated utilizing a pion fuel out of equilibrium. We describe the theoretical framework had to receive the shear and bulk viscosities, the thermal and electric conductivities and the flavour diffusion coefficients of a meson fuel at low temperatures.
This booklet includes the contributions to the thirty fourth Hemophilia Symposium, Hamburg 2003. the most themes are HIV an infection and epidemiology, administration of bleedings in hemophiliacs with inhibitors, orthopedic difficulties and treatment in hemophiliacs, treatment with protein C and pediatric hemostaseology. the quantity is rounded off by means of quite a few unfastened papers and posters on hemophilia, hemophiliacs with inhibitors, thrombophilia and molecular diagnostics.
- Advances in Enzymology and Related Areas of Molecular Biology, Volume 36 (v. 36)
- Care-Related Quality of Life in Old Age: Concepts, Models and Empirical Findings
- Sterile Product Development: Formulation, Process, Quality and Regulatory Considerations
- Disorders of Personality: Introducing a DSM/ICD Spectrum from Normal to Abnormal, Third Edition
- Geospatial Thinking
Additional info for Meningococcal Disease: Methods and Protocols
Commun. Dis. Public Health 1, 54–56. , Hui, F. , and Morrison, D. A. (1995) Characterisation of IS1167, a new insertion sequence in Streptococcus pneumoniae. Plasmid 33, 127–138. , Fomukong, N. , Brown, I. , and Dale, J. W. (1994) Characterisation of IS1110, a highly mobile genetic element from Mycobacterium avium. Mol. Microbiol. 12, 717–724. Mulcahy, G. , Kaminski, Z. , Albanese, E. , and Pierce, M. (1996) IS6110-based PCR methods for the detection of Mycobacterium tuberculosis. J. Clin. Microbiol.
Kaczmarski, E. , and Fox, A. J. (1998) SiaD PCR ELISA for confirmation and identification of PCR Diagnosis 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 39 serogroup Y and W135 meningococcal infections. FEMS Microbiol. Lett. 159, 209–214. , and Olcen, P. (1999). PCR identification of the group A Neisseria meningitidis gene in cerebrospinal fluid. Scand. J. Infect. Dis. 31, 481–483. , Gray, S. J. Kaczmarski, E. , et al. (2000). Evaluation of the applied biosystems automated TaqMan PCR system for the detection of meningococcal DNA.
Consider direct inoculation for antibiotic sensitivity testing e. Consider optochine test (on blood-agar medium) when suspecting pneumococci Consider antigen detection Consider DNA detection sistent suspicion of meningococcal disease. Some of these methods are described in other chapters of this book and comprise antigen-detection methods including latex- and co-agglutination techniques (10); direct immunofluorescence with specific conjugates (3,10); enzyme immunoassays (34,35); and DNA amplification methods like PCR for different target sequences like the 16S rRNA gene (36–38) and the ctrA gene.