By Mary Ann Handel (Eds.)
Even if the method of meiosis is prime to inheritance, strangely little is known approximately the way it really happens. There has lately been a flurry of study job during this sector and this quantity summarizes the advances coming from this paintings. All authors are well-known and revered study scientists on the leading edge of analysis in meiosis. Of specific curiosity is the emphasis during this quantity on meiosis within the context of gametogenesis in better eukaryotic organisms, subsidized up by way of chapters on meiotic mechanisms in different version organisms. the point of interest is on smooth molecular and cytological recommendations and the way those have elucidated basic mechanisms of meiosis. Authors supply easy accessibility to the literature in the event you are looking to pursue subject matters in better intensity, yet experiences are complete in order that this e-book might turn into a typical reference. Key positive factors* complete reports that, taken jointly, supply updated assurance of a speedily relocating box* positive factors new and unpublished details* Integrates learn in diversified organisms to give an summary of universal threads in mechanisms of meiosis* contains considerate attention of parts for destiny research
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Such experiments serve to elucidate the types and rates of recombination events i n humans and mice. These observations in turn provide insight into the role of recornbination in molecular evolution and disease. Nevertheless, we anticipate that important progress in the next few years will come from targeted mutagenesis of genes involved in meiotic recombination. These experiments have been, and will continue to be, guided by the extensive studies done in yeast. Another major advance would be the establishment of a culture system for mammalian gametes that could accurately reproduce the salient events of mammalian meiosis.